Wednesday, September 19, 2018

Nexium & Prilosec - Link to Kidney Failure

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Nexium & Prilosec are drugs called proton pump inhibitors. They are used to treat gastroesophageal reflux disease, by reducing the amount of acid in a person’s stomach. They also may be prescribed to heal acid-related damage to the lining of the esophagus; to reduce stomach ulcers; and to treat stomach infections.

Approximately 15 million Americans use proton pump inhibitors. However, as many as 25% of long-term users could stop taking the medication without suffering increased heartburn or acid reflux, according to researchers at Johns Hopkins University.

the primary use of Nexium and Prilosec is to treat acid reflux
 

Nexium & Prilosec Side Effects

Nexium and Prilosec Side Effects

The most serious potential side effects and risks caused through the use of Nexium & Prilosec are bone fractures, kidney disease, renal failure and heart damage. People who take multiple daily doses for a long period of time (a year or longer), especially those 50 years of age or older, have an increased risk of fractures of the hip, wrist, and spine. Additionally, people who use the drugs appear to have a 20 percent to 50 percent higher risk of chronic kidney disease compared with nonusers.

Less Serious Side Effects
Abdominal pain
Chronic inflammation of the stomach lining
Constipation
Diarrhea
Drowsiness
Dry mouth
Gas
Headaches
Low magnesium levels
Nausea
 

"PPI users [such as Nexium and Prilosec] are at increased risk for heart attack, stroke and renal failure,” says Dr. John P. Cooke, Houston Methodist Research Institute.

It’s very important to tell your doctor if you have any of the following issues: (i) kidney disease; (ii) osteoporosis; (iii) low bone mineral density (osteopenia); or (iv) low levels of magnesium in your blood.

 
Nexium & Prilosec Videos
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Nexium & Prilosec Lawsuits
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To review current information regarding the lawsuits arising out of Nexium and Prilosec related injuries, click Nexium & Prilosec Lawsuit Info, a comprehensive webpage on Nexium & Prilosec maintained by the law firm of Levin Papantonio.

FDA and Scientific Studies Regarding Nexium & Prilosec

Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease

Proton pump inhibitors (PPIs) are among the most commonly used drugs worldwide and have been linked to acute interstitial nephritis. Less is known about the association between PPI use and chronic kidney disease (CKD). . . . Proton pump inhibitor use is associated with a higher risk of incident CKD. To read more, click Journal of American Medical Association

 

PPIs and kidney disease: from AIN to CKD

Proton pump inhibitors (PPIs) are commonly prescribed and available over-the-counter, and are taken by millions of patients around the world, often for many months to years. While PPIs have an excellent overall safety profile, concerns have been raised about adverse renal events, specifically their association with acute interstitial nephritis (AIN). While only a small proportion of patients develop AIN from PPIs, these drugs are now a common cause of drug-induced AIN in the developed world due to their widespread and prolonged use. To read more, click Journal of the American Society of Nephrology

Nexium & Prilosec Recall Information

As of this time, there has not been a recall of Nexium or Prilosec related to kidney damage. However, the investigation into these drugs, from a legal standpoint, are still at the early stages. It often takes many years; tens of thousands of hours of attorney time; and the expense of many millions of dollars before all the facts come out that will lead to a recall.